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Construction and Sharing Mechanism of Bioinformatics Databases: Data Governance Strategies for Cross-Species Comparative Genomics

Author(s)

Yu Ding

Affiliation(s)

Jintan No.1 High School, Changzhou, China

Abstract

With the rapid development of high-throughput sequencing technology, the volume of bioinformatics data has shown explosive growth, and cross-species comparative genomics has become an important means to analyze the laws of life evolution, gene functions and disease mechanisms. However, data heterogeneity, privacy protection requirements and technical barriers have led to a serious phenomenon of data silos, restricting scientific research collaboration and innovation. This paper systematically explores the core issues of cross-species comparative genomics data governance from three dimensions: database architecture design, data governance strategies, and innovation of sharing mechanisms. It proposes solutions based on modular design, distributed storage, and dynamic governance frameworks, and verifies their feasibility by combining global typical cases, providing theoretical support for biomedical data integration and open science.

Keywords

Bioinformatics Database; Cross-Species Comparative Genomics; Data Governance; Distributed Storage; Privacy Protection

References

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